Knee aspiration and high definition MRI for ACL injury Pilot study

• Research type

  Research Study

• Full title

  Pilot study into the structural local molecular environment following an ACL injury

• IRAS ID

  249559

• Contact name

  Stephen McDonnell

• Contact email

  sm2089@cam.ac.uk

• Sponsor organisation

  Cambridge University Hospitals and the University of Cambridge

• Duration of Study in the UK

  0 years, 4 months, 30 days

• Research summary

  The aim of this pilot study is to understand the biological changes that occur within the knee joint following injury to the anterior cruciate ligament (ACL). This will be achieved through aspiration and analysis of the haemarthrosis which fills the knee following injury. We will look at inflammatory and healing responses using DNA, RNA and protein analysis. This, combined with high resolution imaging of the knee and surrounding soft tissue structures, may enable a more patient specific approach to treatment of ACL injury.

• REC name

  London - Chelsea Research Ethics Committee

• REC reference

  19/LO/0781

• Date of REC Opinion

  29 May 2019

• REC opinion

  Further Information Favourable Opinion