KineDMD
Research type
Research Study
Full title
A study of kinematics in Duchenne Muscular Dystrophy
IRAS ID
237875
Contact name
Aldo Faisal
Contact email
Sponsor organisation
Imperial College London
Duration of Study in the UK
1 years, 6 months, 0 days
Research summary
Duchenne Muscular Dystrophy (DMD) is common inherited and life limiting muscle disease of childhood. At present, there is no curative treatment, but a number of exploratory treatment are undergoing experimentation and are in clinical trial stages. Clinical trial designs for DMD currently rely on outcome measures of muscle function and strength, which get evaluated during clinical appointments. Such tests require attendance to hospital appointments and results can be influenced by patient motivation and level of tiredness on the day, or assessors’ skills and instructions. As a consequence, a larger sample size and longer duration of clinical trials are required, often delaying access to new drugs or creating a disincentive for industries to invest in drug development for this condition. In this study novel measurements relying on non-invasive, compact and wireless sensor system will be collected at home and in clinic to determine behavioural markers of movement specific to DMD in the hope to expedite drug development.
REC name
South West - Cornwall & Plymouth Research Ethics Committee
REC reference
18/SW/0012
Date of REC Opinion
5 Mar 2018
REC opinion
Further Information Favourable Opinion