Jolt-Ca Stablemates Trial

  • Research type

    Research Study

  • Full title

    JoLT-Ca A Randomized Phase III Study of Sublobar Resection (SR) versus Stereotactic Ablative Radiotherapy (SAbR) in High Risk Patients with Stage I Non-Small Cell Lung Cancer (NSCLC), The STABLE-MATES Trial

  • IRAS ID

    281607

  • Contact name

    Joel Dunning

  • Contact email

    joeldunning@nhs.net

  • Sponsor organisation

    South Tees Hospital NHS Foundation Trust

  • Clinicaltrials.gov Identifier

    NCT02468024

  • Duration of Study in the UK

    3 years, 0 months, 0 days

  • Research summary

    This is a phase III randomized trial comparing sublobar resection to SAbR radiation in high risk stage I lung cancer patients. The purpose of the study is to confirm which procedure is more effective and safer. In order to confirm this patients will be 1:1 randomised to one of these procedures and then subsequently monitored to assess their health outcomes (specifically survival data and side effects) which will include visits 4 weeks after treatment then every 3 months for 2 years, then every 6 months for 3 more years. If patients decline to be randomised to one of the treatments we will still ask if they are happy for their data to be collected to aid the study analysis.

  • REC name

    East of Scotland Research Ethics Service REC 2

  • REC reference

    21/ES/0083

  • Date of REC Opinion

    20 Oct 2021

  • REC opinion

    Further Information Favourable Opinion