JEWELACL Study: RCT comparing hamstrings and hybrid artificial graft
Research type
Research Study
Full title
The Jewel ACL Study: Feasibility Randomised Controlled Trial Comparing the Outcomes of the Auto graft ACL Reconstruction (Using Hamstring Tendon) to a Hybrid Artificial (JewelACL) and autograft ACL Reconstruction
IRAS ID
253318
Contact name
Neil Jain
Contact email
Sponsor organisation
Research & Innovation Salford Royal NHS Foundation Trust Northern Care Alliance NHS Group
Duration of Study in the UK
3 years, 5 months, 28 days
Research summary
This trial will compare an artificial hybrid graft with the patients own tendon graft for ACL reconstruction. Currently we do not have enough data to suggest if one graft is better than the other or the same. The theory is that there may be less pain for the patient with hybrid artificial grafts and quicker recovery to exercise than tendon grafts.
The artificial graft is made of polyester and promotes own cell growth by providing a scaffold. The study will last 3 and a half years to allow 18 months of recruitment and 2 years follow up. We will follow up patients in clinic and via questionnaires. This study will be carried out in clinic at NHS hospitals and functional assessment will be carried out at the Manchester Institute for Health and Performance (MIHP). All patients over the age of 18 that attend clinic with anterior cruciate ligament rupture will be considered unless it is a revision procedure or the patient has a BMI over 40.REC name
London - Surrey Research Ethics Committee
REC reference
19/LO/1429
Date of REC Opinion
18 Nov 2019
REC opinion
Further Information Favourable Opinion