IV Prev: Device to prevent catheter infection
Research type
Research Study
Full title
IV Prev, a non-invasive medical device automatically applying antiseptic to prevent catheter infections
IRAS ID
156349
Contact name
Angus Watson
Contact email
Sponsor organisation
NHS Highland
Duration of Study in the UK
0 years, 0 months, 30 days
Research summary
This healthy volunteer study aims to provide data to support the development of research studies for a medical device. Catheter insertion into the skin allows bacteria to enter the blood by formation of a layer around the catheter entry point. These bacteria can cause infections which can cause inconvenience to patients, increase their hospital stay and in some cases can be fatal. Once a biofilm is formed, it becomes difficult to break this layer. The alternative is to change catheters, which is a cumbersome and expensive process. Research indicates biofilm usually takes 7-8 hours to form. Our aim is to prevent the biofilm formation by killing bacteria on the skin before it forms a biofilm.
For this we have developed a medical device, IV Prev, which is non-invasive and automatically applies existing antiseptic externally on the wound to kill these bacteria. Antiseptic is applied at regular intervals instead of having a constant inflow of antiseptic.
The aim of this study is to use healthy volunteers to participate in a pilot study to find out if timed application of antiseptic can kill and prevent further growth of bacteria on skin.
Healthy volunteers will get three IV Prev devices placed on unbroken skin on one arm, applying antiseptic once in 6hrs, 12hrs and 24hrs, for 12 days with a control on the same arm consisting of participants having a non-coated dressing. All of these sites will be covered by a waterproof covering when the volunteers wish to wash their arm.
REC name
North of Scotland Research Ethics Committee 1
REC reference
14/NS/1052
Date of REC Opinion
10 Nov 2014
REC opinion
Further Information Favourable Opinion