Ischaemic preconditioning training in Type 2 Diabetes

• Research type

  Research Study

• Full title

  Does daily ischaemic preconditioning improve blood vessel function and insulin sensitivity in type 2 diabetes mellitus

• IRAS ID

  156219

• Contact name

  Helen Jones

• Contact email

  H.Jones1@ljmu.ac.uk

• Research summary

  Occlusion (cuff inflation to a pressure that reduces blood flow) using a blood pressure cuff on the upper arm for 5 mins followed by recovery (cuff deflation so blood flows normally gain), is known as ischemic preconditioning (IPC). An intervention consisting of 4 cycles of 5 min arm occlusion followed by 5 min periods of recovery on a daily basis can improve blood vessel function. This is a simple and easily applicable intervention that immediately improves the blood vessels capacity to deliver blood to an organ (e.g. heart or the muscle). However, it is currently unknown if a daily IPC can improve blood vessel function in patients with type 2 diabetes mellitus (T2DM) and if it will aid in improving blood glucose control. Therefore, the purpose of this study is to investigate if daily IPC g for 7 days can improve blood vessel function and blood glucose control in T2DM.

• REC name

  North West - Liverpool Central Research Ethics Committee

• REC reference

  14/NW/1208

• Date of REC Opinion

  27 Oct 2014

• REC opinion

  Further Information Favourable Opinion