Investigation into the Speed of Raft formation in healthy volunteers

  • Research type

    Research Study

  • Full title

    A randomised, single-dose, double-blind, 2-way crossover, single-centre study to compare the speed of raft formation assessed by gamma scintigraphy in healthy volunteers following administration of Gaviscon® Strawberry Flavour Tablets (2 x 250 mg) and placebo tablets (2 x 250 mg).



  • Contact name


  • Sponsor organisation

    Reckitt Benckiser Healthcare (UK) Ltd

  • Eudract number


  • ISRCTN Number


  • Research summary

    The purpose of the study is to determine how fast a foamy layer (called a ??raft??) is formed in the stomach following a dose of Gaviscon© Strawberry Flavour Tablets. In order to see how fast the ??raft?? is formed after taking Gavison© Strawberry Flavour Tablets, a technique called Gamma Scintigraphy will be used. Gamma Scintigraphy is a technique used to capture the movement of a radioactive tracer inside the body. The study consists of 1 screening visit, 2 treatment visits and 1 follow-up visit. This study has a randomised and blinded design. It is randomised because each subject will receive both Gaviscon© Strawberry Flavour Tablets and Placebo Tablets over the 2 treatment visits in a randomised order.

  • REC name

    Wales REC 2

  • REC reference


  • Date of REC Opinion

    19 Jul 2012

  • REC opinion

    Favourable Opinion