Investigating the role of IL-33 on human vessels

• Research type

  Research Study

• Full title

  Investigating the role of Interleukin-33 on human vessels

• IRAS ID

  275995

• Contact name

  Ian Wilkinson

• Contact email

  ibw20@cam.ac.uk

• Sponsor organisation

  Cambridge University Hospitals NHS Foundation Trust and University of Cambridge

• Duration of Study in the UK

  1 years, 5 months, 1 days

• Research summary

  The aim of this study is to investigate the role of the protein IL-33 in human blood vessels. IL-33 is involved in the development of cardiovascular and pulmonary diseases and previous animal and human studies suggest that IL-33 may play a role in regulating vascular tone and permeability, with consequences for vascular health.

  Will use wire myography to assess the effect IL-33 has on vascular tone and permeability of resistance/pulmonary vessels.

• REC name

  East Midlands - Leicester Central Research Ethics Committee

• REC reference

  21/EM/0053

• Date of REC Opinion

  18 Mar 2021

• REC opinion

  Further Information Favourable Opinion