Investigating the function of the immune system during cancer v1

  • Research type

    Research Study

  • Full title

    A study to investigate the effects of cancer and cancer treatment on the immune system over time

  • IRAS ID

    122276

  • Contact name

    Poulam Patel

  • Contact email

    poulam.patel@nottingham.ac.uk

  • Sponsor organisation

    University of Nottingham

  • Research summary

    This study will investigate how the immune system changes in individual patients due to cancer and during treatment for cancer. We know that the immune system can affect how a cancer grows, and targeting the immune system holds promise for treatment of cancer. To do this effectively, we need to understand how the immune system changes during the course of a cancer and the treatments we currently use.
    Eligible participants would include adults with cancer/a previous cancer under followup at Nottingham University Hospitals. The study will consist of small (10-20ml) serial blood samples taken from participants during their followup for/treatment of cancer. Permission will also be sought to use tumour samples previously removed and removed during the course of the study as part of routine clinical care. Other than blood sampling, participants will not need to undergo any additional procedures. We will use healthy volunteers who will provide blood samples to act as a control group.

  • REC name

    East Midlands - Nottingham 1 Research Ethics Committee

  • REC reference

    13/EM/0218

  • Date of REC Opinion

    20 Jun 2013

  • REC opinion

    Favourable Opinion