Investigating how childhood tumours and congenital disease develop
Research type
Research Study
Full title
Investigating how childhood tumours and congenital disease develop
IRAS ID
207523
Contact name
Sam Behjati
Contact email
Sponsor organisation
Wellcome Trust Sanger Institute
Duration of Study in the UK
4 years, 5 months, 28 days
Research summary
Every cell and every organ in the human body derives from a fertilised egg. As the fertilised egg divides, a human being develops and grows. The process of how the fertilised egg divides and forms a human being is very sophisticated and is directed by the genetic information, the DNA, that is present in every cell.
When errors, mutations, in the DNA code arise, the orderly process of human development can be disrupted. This can lead to the development of tumours during childhood and congenital diseases (that is, abnormalities that children are born with).
The aim of this study is to define exactly which DNA errors underpin childhood tumours and congenital diseases.
REC name
East of England - Cambridge Central Research Ethics Committee
REC reference
16/EE/0394
Date of REC Opinion
28 Dec 2016
REC opinion
Further Information Favourable Opinion