Investigating Corticosteroid Responsiveness

  • Research type

    Research Study

  • Full title

    An evaluation of increased doses of steroid in poorly controlled asthma

  • IRAS ID

    207761

  • Contact name

    Tim Harrison

  • Contact email

    tim.harrison@nottingham.ac.uk

  • Sponsor organisation

    University of Nottingham

  • Duration of Study in the UK

    1 years, 0 months, 0 days

  • Research summary

    Most people with asthma take an inhaled steroid to control their symptoms. A common question in clinical practice is whether more steroid would be of benefit? To determine this patients are often prescribed a month of high dose inhaled steroids or a two-week course of oral steroids to document steroid responsiveness. The purpose of this study is to describe the features of responders and non-responders to an increased dose of steroid and establish if it is possible to identify patients who will and will not respond to increased doses of steroids in terms of clinical measurements and biomarkers.

  • REC name

    London - Surrey Research Ethics Committee

  • REC reference

    16/LO/1828

  • Date of REC Opinion

    6 Oct 2016

  • REC opinion

    Further Information Favourable Opinion