Intraoperative UltraSound in ileocolic Crohn's disease
Research type
Research Study
Full title
Assessing the feasibility and safety of using Intraoperative UltraSound in ileocolic Crohn’s disease. The IUSS CROHN feasibility study
IRAS ID
248690
Contact name
Valerio Celentano
Contact email
Sponsor organisation
Portsmouth Hospitals NHS Trust
Duration of Study in the UK
0 years, 11 months, 31 days
Research summary
Crohn’s disease is a chronic inflammatory condition that can involve any part of the gastrointestinal system and it is estimated that 115.000 patients are affected in the United Kingdom. The medical and surgical treatment of Crohn’s disease aims to improve patients’ quality of life and treat complications that can occur during the course of the disease, such as narrowing of the bowel (bowel strictures causing bowel obstruction), bleeding, and serious infection of the abdomen caused by a perforation of the bowel (intra-abdominal abscesses and fistulae). 80% of patients will require surgery during their lifetime, and because Crohn’s disease is a chronic condition many patients may require surgery again for recurrence of disease. For these reasons, it is of paramount importance that the medical and surgical treatment concentrates on preserving as much as possible the amount of healthy bowel left in every patient.
This study is looking at patients who require surgery for Crohn’s disease affecting the last part of the small bowel (terminal ileum).
In the IUSS CROHN study “A feasibility study on the use of Intraoperative UltraSound in ileocolic Crohn’s disease”, the Ultrasound will be used intraoperatively, to assess the extent of Crohn's disease in the small bowel, to guide the surgeon towards a more precise treatment.The aim of this study is to evaluate if an intraoperative protocol for Ultrasound scan is feasible and safe in patients undergoing elective surgery for ileocolic Crohn's Disease. The results of this study could guide the development of a larger randomised trial.
REC name
South West - Frenchay Research Ethics Committee
REC reference
18/SW/0213
Date of REC Opinion
13 Sep 2018
REC opinion
Favourable Opinion