Intraocular pressure after lower lid lateral tarsal strip v3.3
Research type
Research Study
Full title
Intraocular pressure after lower lid lateral tarsal strip
IRAS ID
219266
Contact name
Sarju Athwal
Contact email
Sponsor organisation
Maidstone and Tunbridge Wells NHS Trust
Duration of Study in the UK
0 years, 6 months, 2 days
Research summary
The aim of this study is to assess whether lower lid tightening surgery (lateral tarsal strip, LTS) causes an increase in the pressure inside the eye (intraocular pressure, IOP). LTS is the most common operation to correct drooping or laxity of the lower eyelid (ectropion). This involves shortening and tightening the lower eyelid. Lower eyelid laxity tends to be more common in older patients. Glaucoma is a condition where the optic nerve undergoes irreversible damage, frequently due to raised IOP. Uncontrolled glaucoma can lead to permanent loss of vision. Glaucoma is also more common in older patients. Therefore, it is important to know if the surgery is having any effect on IOP as this could cause progression of pre-existing glaucoma.
This study will look at the effect of LTS surgery on the IOP of healthy patients, who do not already have glaucoma. We will recruit suitable participants from the Oculoplastic clinic at the Eye department in Maidstone Hospital. We are aiming to recruit about 30 participants. These participants will undergo a standard pre-operative examination, including measurement of IOP, and then the LTS surgery. The IOP will then be measured again immediately post-operatively, and then at 2 weeks and 3 months. Most of this is no different to the standard care pathway patients currently undergo. The only additional step the study participants would undergo will be the examination and IOP measurement at 3 months. Normally, patients having LTS would be discharged at the 2 week post-operative appointment.
REC name
East Midlands - Nottingham 2 Research Ethics Committee
REC reference
17/EM/0045
Date of REC Opinion
23 Jan 2017
REC opinion
Favourable Opinion