Interventions for Malignant Pleural Effusions impact on fatigue study
Research type
Research Study
Full title
Do Interventions for Malignant Pleural Effusions (MPE) impact on patient reported Fatigue levels? A questionnaire based pilot study (IMPE-F study)
IRAS ID
276451
Contact name
Donna Wakefield
Contact email
Sponsor organisation
Northumbria Healthcare NHS Foundation Trust
Duration of Study in the UK
0 years, 9 months, 1 days
Research summary
The lungs are covered by two thin membrane called the pleura. The space between these layers is called the pleural space. When fluid builds up here it is called a pleural effusion. This is commonly due to cancer, which is called a Malignant Pleural Effusion (MPE). Different procedures can be used to treat an MPE such as putting a tube into the pleural space to let the fluid drain out. Other methods involve putting special chemicals into the pleural space to seal the two layers together so that there is no longer a space for the fluid to collect within. \n \nThe presence of an MPE is a sign of advanced disease and so it is vital to consider ways to improve quality of life in this patient group. Breathlessness is the most common symptom in patients with a pleural effusion and so previous research has focused on how the different treatment options can improve this. Fatigue is also a very common in patients with cancer. This study aims to find out whether treating MPEs can also help improve patient fatigue levels. \n\nPatients are referred to the specialist “pleural service“ at North Tyneside Hospital or Wansbeck Hospital (Northumbria Healthcare NHS Foundation Trust). At this clinic it will be decided which treatment for the MPE would be best for the individual; this study will have no influence on which treatment is chosen. The doctor will then offer the patient the opportunity to be involved with this study. This involves asking the patient to answer 13-questions about their level of fatigue over the past 7 days. This questionnaire would be done before treatment of their MPE and then repeated via telephone after 7,14 & 30 days. Other information about the patient which could also have an impact on fatigue levels will also be gathered.\n\n\n
REC name
Yorkshire & The Humber - Leeds East Research Ethics Committee
REC reference
20/YH/0224
Date of REC Opinion
31 Jul 2020
REC opinion
Further Information Favourable Opinion