Interstim Amplitude study

  • Research type

    Research Study

  • Full title

    Interstim Amplitude study

  • IRAS ID

    236497

  • Contact name

    Mahreen Pakzad

  • Contact email

    mahreen.pakzad@nhs.net

  • Sponsor organisation

    Medtronic

  • Clinicaltrials.gov Identifier

    NCT03335761

  • Duration of Study in the UK

    1 years, 3 months, 16 days

  • Research summary

    The indication for this study is overactive bladder (OAB), Symptoms of OAB include an increased urge to urinate that may lead to unconscious leakage of urine. The patients enrolled in this study will receive a Medtronic Interstim System to treat these symptoms. This system is routinely available as part of normal clinical care and is not experimental. \nThe purpose of this prospective, multicenter, randomized, single‐blind feasibility study is to gather information about how the settings of the InterStim system will affect OAB symptoms. The specific setting that is being investigated in this study is called amplitude. Amplitude refers to the intensity level at which the InterStim device is set. This study will investigate the efficacy and quality of life of patients who have OAB under 3 different amplitude settings (sub‐sensory amplitudes of 50% and 80% of sensory threshold and sensory threshold)

  • REC name

    London - Bloomsbury Research Ethics Committee

  • REC reference

    18/LO/0150

  • Date of REC Opinion

    20 Feb 2018

  • REC opinion

    Favourable Opinion