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Inter-field strength agreement of CMR derived strain version 1.0

  • Research type

    Research Study

  • Full title

    Inter-field strength agreement of myocardial strain measurements using cardiovascular magnetic resonance imaging

  • IRAS ID

    270415

  • Contact name

    Gerry McCann

  • Contact email

    gpm12@le.ac.uk

  • Sponsor organisation

    University of Leicester

  • Duration of Study in the UK

    0 years, 6 months, 1 days

  • Research summary

    Magnetic Resonance Imaging (MRI) scanners create a strong magnetic field around the body to produce a detailed picture of parts of the body. An MRI scan of the heart gives doctors lots of information about the way the heart looks and works. Different strengths of magnets can be used in an MRI scanner and this can affect the pictures that are produced. To scan the heart, we mainly use two different magnet field strengths (1.5 tesla (T) and 3T). It is currently unclear when we scan the heart using these different field strengths, if the measurements we get that tell us how well the heart squeezes and relaxes (known as ’myocardial strain’) will be the same between them. In this study, we are proposing to investigate if the measurements we get of myocardial strain using 1.5T and 3T MRI scanners are different or if they can be used interchangeably. To do this, we are going to recruit twenty healthy people without heart disease to have two MRI scans on the same day. The order that they have their scan (either on a 1.5T MRI scanner first or a 3T MRI scanner first) will be decided randomly; they will then have a scan on the other MRI scanner. All the images will then be analysed to provide measurements of myocardial strain. This will allow us to assess if there is agreement between the myocardial strain results at the two MRI field strengths.

  • REC name

    Yorkshire & The Humber - Bradford Leeds Research Ethics Committee

  • REC reference

    19/YH/0392

  • Date of REC Opinion

    6 Nov 2019

  • REC opinion

    Favourable Opinion