Intellatip MiFi Catheter to Optimise Left Atrial Ablation & Mapping
Research type
Research Study
Full title
The Utilisation of the Intellatip MiFi Open Irrigation Catheter to Optimise AF Ablation & Mapping of Atrial Arrhythmias.
IRAS ID
160356
Contact name
Pier D Lambiase
Contact email
Duration of Study in the UK
2 years, 2 months, 30 days
Research summary
Catheter ablation is now the most effective and recommended treatment for atrial fibrillation (AF) when drugs fail to treat patient’s symptoms. However, this procedure still has a significant failure rate.
It is thought that in catheter ablation of AF, some of the ablation therapy lines performed to block the abnormal electric activity exiting from the pulmonary veins & triggering AF, end up developing gaps (i.e. they become incomplete). These gaps may not be detected by current catheter technologies, but may be identified by an improved catheter with more electrodes (4 mini electrodes – ME), placed closer to the tip of the catheter (2mm rather than 8.6mm like in standard catheters) which provide higher resolution (the Intellatip MiFi open-irrigated (OI) catheter).This study, being performed only at The Heart Hospital, has 2 aims:
1) To assess heart’s electrical signals using the ME of the new catheter to assess lines after ablation and detect gaps not seen by a standard catheter, before and after administration of a drug (adenosine) for improving gap detection.15 patients with paroxysmal AF (short duration episodes) and 15 patients with persistent AF (long duration episodes) will be included.
2) To record the electrical activity of the heart while ablating 15 patients with atrial tachycardia arising either during ablation of persistent AF or as a consequence of previous AF ablation.REC name
London - Harrow Research Ethics Committee
REC reference
15/LO/0175
Date of REC Opinion
15 Jun 2015
REC opinion
Further Information Favourable Opinion