INTEGRATE - Transitions between renal replacement therapies
Research type
Research Study
Full title
INTEGRATE - Transitions between renal replacement therapies: patients' and staffs' experience of transitioning from peritoneal dialysis to haemodialysis.
IRAS ID
237901
Contact name
Gill Combes
Contact email
Sponsor organisation
University of Birmingham
Duration of Study in the UK
0 years, 9 months, 31 days
Research summary
Patients with end stage renal disease (ESRD) have different options to replace the function of their failing kidneys. Over the years, the search for the most optimal renal replacement therapy (RRT) has progressively been replaced by the understanding that most patients will use different modalities at different time points of their disease. This model has been termed "integrated care" because it intends to consider treatment pathways rather than individual RRT techniques. In its original format, it involved the initiation of peritoneal dialysis (PD) followed by a timely switch to in-centre haemodialysis (HD). Available literature suggests that at present, transition between the different modalities is poorly coordinated, causing harm to patients.
This research focuses on exploring the transition from PD to HD from the perspectives of patients, caregivers, and healthcare staff. There are two main scenarios in which patients may transition from PD to HD (planned and unplanned) and we will interview a broad selection of patients to encompass both routes. There is likely a difference between the two transition types. Planned transitions should cause less stress if done well, and unplanned transitions should be manageable and show a clear treatment pathway that mitigates against distress as much as possible.
Interviews with all participants will be conducted across three NHS Trusts in the UK and in three hospitals in and around Brisbane, Australia. This international collaboration will allow us to compare the different healthcare systems for similarities and differences. We will also draw out best practice from both systems and suggest ways to improve the transition from PD to HD in all locations.REC name
London - London Bridge Research Ethics Committee
REC reference
18/LO/0974
Date of REC Opinion
1 Jun 2018
REC opinion
Favourable Opinion