Insight V5

• Research type

  Research Study

• Full title

  The acute and long-term psychological and brain effects of psilocybin in healthy volunteers

• IRAS ID

  199634

• Contact name

  Becky Ward

• Contact email

  becky.ward@imperial.ac.uk

• Sponsor organisation

  Imperial College London and Imperial College NHS Trust

• Duration of Study in the UK

  1 years, 11 months, 6 days

• Research summary

  This will be a one-arm, single-blind, fixed order, within-subjects study in up to 25 healthy volunteers. All volunteers will attend a screening visit before being enrolled in the study. The volunteers will then undergo: 1) baseline visit (inc. fMRI); 2) 1mg psilocybin (placebo) dosing session (inc. EEG); 3) a one-day post placebo visit (inc. fMRI); 4) 4 weeks post-placebo follow-up visit; 5) 25mg psilocybin dosing session (inc. EEG); 6) one day post 25mg psilocybin visit; 7) 4 weeks post 25mg psilocybin follow-up visit (inc. fMRI & primary endpoint).

• REC name

  London - Surrey Research Ethics Committee

• REC reference

  18/LO/0483

• Date of REC Opinion

  21 May 2018

• REC opinion

  Further Information Favourable Opinion