Injectate Distribution in Cadaveric Lateral Elbow Tendons
Research type
Research Study
Full title
Evaluation of the Spread of Injectate after Ultrasound-Guided Lateral Elbow Injection and Assessment of ’Triceps on’ surgical exposure
IRAS ID
218788
Contact name
Jonathan Evans
Contact email
Sponsor organisation
University of Exeter
Duration of Study in the UK
0 years, 2 months, 1 days
Research summary
This study aims to assess the distribution of injection fluid in the Extensor Carpi Radialis Brevis (ECRB) Tendon in cadaveric elbow specimens. This is the tendon that is injected when patients are suffering from Tennis Elbow. \nOur Objectives are to:\n\n1)\tAdminister 1 or 3mls of stained injectate using ultrasound guidance\n2)\tUsing both single injection and fenestration (peppering) techniques\n3)\tAssessing proximodistal (horizontal) and cross-sectional (width) distribution of intra-tendenous injectate\n4)\tAssess the area of contamination of surrounding tissue following injection\n\nThis study aspires to inform research aiming to ascertain an optimum volume and administration protocol for intra-tendenous ECRB injection. Only when we achieve the above objectives can further studies evaluate the ideal concentration of active injection constituents to ensure therapeutic effect. \n\nAs part of the surgical exposure of the tendon and surrounding structures, we will also be assessing the utility of two popular surgical approaches used in elbow replacements. Our aim is to assess the ability of both the ’Morrey approach’ and ’Triceps preserving approach’ to provide exposure to the ulnar articular surface and assist in the implantation of the elbow replacement component.
REC name
North West - Preston Research Ethics Committee
REC reference
17/NW/0065
Date of REC Opinion
12 Jan 2017
REC opinion
Favourable Opinion