Influence of Antioxidant Supplementation During Exercise Heat Stress
Research type
Research Study
Full title
Influence of Antioxidant Supplementation on Oxidative Stress and Thermal Tolerance During Exercise Heat Stress
IRAS ID
145396
Contact name
Nursyuhada Mohd Sukri
Contact email
Sponsor organisation
University of Bath
Research summary
Regular exercise is an important part of a healthy lifestyle. people who lead an active life are more likely to live longer and less likely to develop serious diseases such a heart disease, cancer and diabetes.
However, all forms of exercise cause some oxidative stress. most researchers agree that moderate exercise produces healthy amounts of oxidative stress leading to healthy adaptations, but some resea4chers also agree that long, intense exercise, particularly in hot environments (especially endurance training) may cause excessive oxidative stress and damage some tissues. The term "oxidative stress" describes the luck of equilibrium between the production of free radicals and the antioxidant protective capacity in a given organism. Free radicals of oxygen are a natural byproduct of metabolite within the body, they cause cellular damage and breakdown the structure DNA.
There are good epidemiological data to suggest that diet rich in foods that are naturally high in antioxidants is associated with better heath outcomes. Antioxidants work to eliminate the oxidative stress by neutralizing free radicals when they develop, preventing the cell damage (intramuscular).
By investigating the role of antioxidant supplementation in exercise induced oxidative stress, we hope to learn more about these interactions and the potential benefits of supplementation, thereby develop effective methods for improving human health and/or performance in response to exercise induced oxidative stress.
REC name
South West - Frenchay Research Ethics Committee
REC reference
14/SW/0098
Date of REC Opinion
26 Jun 2014
REC opinion
Further Information Favourable Opinion