INfLUENCE-HD

  • Research type

    Research Study

  • Full title

    INfLUENCE-HD: Influencing Huntington's disease monitoring with remote assessments and biomarkers

  • IRAS ID

    323937

  • Contact name

    Lauren Byrne

  • Contact email

    lauren.byrne.14@ucl.ac.uk

  • Sponsor organisation

    University College London

  • Clinicaltrials.gov Identifier

    Z6364106/2025/08/17, UCL Data Protection Registration number; 183580, EDGE (Sponsor) number

  • Duration of Study in the UK

    1 years, 2 months, 29 days

  • Research summary

    INfLUENCE:HD is the first comprehensive observational research program that incorporates a multi-national, longitudinal, investigation of Huntington’s Disease (HD) with a major focus on Juvenile HD (JHD). This study aims to validate blood based biomarkers and explore other peripheral biosamples for the identification of novel biomarkers with potential for remote quantification.
    This has the potential to transform disease monitoring, prognosis and therapeutic development within HD and JHD, but also within Neurology specialist care across the spectrum of many neurological diseases.

  • REC name

    East of England - Cambridge South Research Ethics Committee

  • REC reference

    26/EE/0131

  • Date of REC Opinion

    21 May 2026

  • REC opinion

    Further Information Favourable Opinion