Incidence of CRMO in the UK and ROI; version 1.0
Research type
Research Study
Full title
Incidence of Chronic Recurrent Multifocal Osteomyelitis (CRMO) in the United Kingdom (UK) and Republic of Ireland (ROI)
IRAS ID
270686
Contact name
Chenqu Suo
Contact email
Sponsor organisation
Cambridge University Hospitals NHS Foundation Trust
Duration of Study in the UK
2 years, 4 months, 1 days
Research summary
Chronic Recurrent Multifocal Osteomyelitis (CRMO) is a rare disease where a patient's immune system attacks their bones by mistake, causing bone pain and swelling. It occurs primarily in children and teenagers. It can be very painful for some children with serious complications such as spine fracture. Though first described over four decades ago, we still do not know how common CRMO is. There is also a delay to diagnosis due to under-recognition.
Our study aims to capture all new cases of CRMO by reaching out to all paediatric consultants and paediatric orthopaedic surgeons in the UK and Ireland. We can then determine how common CRMO is, who is involved in the care and this will guide resource allocation and service planning. We would also promote awareness of CRMO among general paediatricians and orthopaedic surgeons by asking them about it. In turn, patients will be diagnosed earlier in the future, with earlier treatment and fewer complications.
REC name
London - Central Research Ethics Committee
REC reference
20/LO/0195
Date of REC Opinion
6 Mar 2020
REC opinion
Favourable Opinion