In vitro platelet activation in Asian subjects
Research type
Research Study
Full title
Measuring the effect of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on in vitro activation of platelets from healthy Asian subjects versus Asian subjects with T2DM
IRAS ID
240882
Contact name
Baukje de Roos
Contact email
Sponsor organisation
University of Aberdeen
Duration of Study in the UK
0 years, 9 months, 24 days
Research summary
Blood platelets are very small blood cells that help to form clots to stop any bleeding. In order to do this, platelets first become activated, before aggregating together to form a plug. Too much platelet activation, however, can be a risk factor for heart disease. Dietary compounds, such as omega-3 fatty acids from fish, can help to maintain the right balance of allowing platelet to aggregate where necessary, but at the same time protect blood platelets from becoming too ‘activated’. The latter may be important, especially in people with type 2 diabetes mellitus, as they generally have higher baseline levels of platelet activation.
In this study we will assess whether omega-3 fatty acids can lower baseline levels of platelet activation in bloods obtained from healthy Asian subjects, and in bloods obtained from Asian subjects who have type 2 diabetes mellitus.REC name
London - Camden & Kings Cross Research Ethics Committee
REC reference
18/LO/0301
Date of REC Opinion
16 Feb 2018
REC opinion
Favourable Opinion