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In-house Donation of Saliva for Oral Health Research

  • Research type

    Research Study

  • Full title

    Donation of Saliva for in-vitro evaluation of the effects of a Sodium Tripolyphosphate-containing toothpaste on stain prevention



  • Contact name

    Alice Bordas

  • Contact email

  • Sponsor organisation

    GSK Consumer Healthcare

  • Research summary

    This study will involve the collection of saliva samples from human subjects for use in Oral Care Research. The saliva will be used in a subsequent in vitro evaluation of the effects of toothpaste containing Sodium Tripolyphosphate on stain prevention. The use of human saliva will allow research scientists to duplicate in vitro the conditions found in the mouth.
    Saliva donation will take place at the In-house Clinical facilities at GSK Consumer Healthcare Weybridge. Subjects will be recruited from GSK employees.
    Each person will visit the clinic on two occasions. The first visit will last approximately 35 min, and the second visit will last 15 min. Donors will be donating a maximum of 10ml of saliva per visit.
    Each sample will be numbered at the time of collection and logged into a 'saliva sample tracking log' for the purposes of traceability of human biological material. This log will be used to track the samples until their disposal.
    The sample numbers will not be traceable to the donors.
    The saliva samples will be pooled into a single sample before their use in the laboratory.

  • REC name

    London - Bromley Research Ethics Committee

  • REC reference


  • Date of REC Opinion

    10 Jul 2014

  • REC opinion

    Favourable Opinion