Improving the efficacy of human CAR-T cells

• Research type

  Research Study

• Full title

  Improving the efficacy of human CAR-T cells

• IRAS ID

  334858

• Contact name

  Beatriz Saenz

• Contact email

  beatriz.saenz@babraham.ac.uk

• Sponsor organisation

  Babraham Institute

• Duration of Study in the UK

  1 years, 11 months, 31 days

• Research summary

  Chimeric Antigen Receptor T (CAR-T) cell therapy has been successful in the treatment of blood tumours. However, similar success has not been observed in solid tumours due to the hostile tumour microenvironment and tumour heterogeneity. This research project aims to improve the efficiency of CAR-T cells to build up the next generation of cell therapy in solid tumours.

• REC name

  West Midlands - Edgbaston Research Ethics Committee

• REC reference

  24/WM/0027

• Date of REC Opinion

  26 Jan 2024

• REC opinion

  Favourable Opinion