Improving Diabetic Education in Adults with Cystic Fibrosis (IDEA-CF)
Research type
Research Study
Full title
A Prospective Study Assessing the Effect of Improving Diabetic Education in Adults with Cystic Fibrosis (IDEA-CF)
IRAS ID
194098
Contact name
Edward Nash
Contact email
Sponsor organisation
Heart of England NHS Foundation Trust
Duration of Study in the UK
0 years, 6 months, 1 days
Research summary
Cystic fibrosis (CF) is the most common life-threatening inherited condition in the Caucasian population, causing premature death due to progressive lung disease. CF also causes damage to the pancreas, resulting in an inability to digest food normally. In a proportion of patients, progressive damage to the pancreas causes reduced secretion of insulin, resulting in CF-related diabetes (CFRD). CFRD is a distinct type of diabetes, with features in keeping with both type 1 and type 2 diabetes and affects approximately 40% of adults with CF. CF patients with CFRD have inferior health outcomes compared to those without CFRD, with an increased risk of chest infections and worse prognosis.
Poor diabetic control is a major problem and is associated with potentially serious consequences including damage to the kidneys (renal failure), eyes (blindness) and blood vessels (peripheral vascular disease). Lack of patient knowledge is thought to be one of the major reasons for poor diabetic control and educational programmes have been developed to help patients with type 1 and type 2 diabetes. However, there are currently very limited educational resources available to people with CFRD.
The Beta cell Education Resources for Training in Insulin and Eating (BERTIE) programme is a well established intervention developed for people with type 1 diabetes. BERTIE is largely relevant to people with CFRD, but due to the complexity of the co-morbidities affecting people with CF, it is not completely appropriate. We have therefore adapted BERTIE to be relevant to people with CF and in the process have developed BERTIE-CF.
This randomised controlled study includes 20 patients with CFRD, with 10 patients being allocated to receive BERTIE-CF and 10 patients being allocated to receive standard care. We will assess diabetic control, lung function, body weight, anxiety, depression, knowledge and patients' perception of the programme in both groups.
REC name
West Midlands - South Birmingham Research Ethics Committee
REC reference
17/WM/0233
Date of REC Opinion
29 Jun 2017
REC opinion
Favourable Opinion