IMPRINT v1

  • Research type

    Research Study

  • Full title

    Immune Profiling in Early Cognitive Disorders

  • IRAS ID

    297391

  • Contact name

    John O'Brien

  • Contact email

    john.obrien@medschl.cam.ac.uk

  • Sponsor organisation

    Cambridgeshire and Peterborough NHS Foundation Trust

  • Duration of Study in the UK

    5 years, 0 months, 1 days

  • Research summary

    There is increasing interest in the role that neuroinflammation plays in the onset and progression of neurodegenerative cognitive disorders. This study will collect blood, saliva, urine and spinal fluid samples in people with mild cognitive impairment, Alzheimer’s disease and Lewy body dementia as well as similarly aged healthy control volunteers. Immune changes in these disorders will be explored to identify to what extent they differ, their impact on clinical symptoms and disease progression and how they change over time.

  • REC name

    North West - Preston Research Ethics Committee

  • REC reference

    21/NW/0314

  • Date of REC Opinion

    22 Dec 2021

  • REC opinion

    Further Information Favourable Opinion