IMPERIUM (IOQL)

  • Research type

    Research Study

  • Full title

    Protocol: F3Z-MC-IOQL An Individualized treatMent aPproach for oldER patIents: A Randomized, controlled, stUdy in type 2 diabetes Mellitus (IMPERIUM)

  • IRAS ID

    143497

  • Contact name

    Simon Heller

  • Contact email

    s.heller@sheffield.ac.uk

  • Sponsor organisation

    Eli Lilly and Company

  • Eudract number

    2013-001473-24

  • Research summary

    The number of older patients with Type 2 Diabetes in many developed and developing countries is increasing. Older patients with Type 2 Diabetes need more complicated care due to their frailty and the amount of them who have other long-term medical conditions in addition to their Diabetes that require treatment. At the moment there are no official guidelines allowing for treatments to be prescribed to these patients based on evidence of how well these treatments may have worked previously in this patient group.

    This study will compare 2 different ways of treating Type 2 Diabetes in this patient group. ’Strategy A’ and ’strategy B’ will work in different ways to treat the participants Diabetes. Both treatment strategies will use drugs that are already approved and marketed for use in Diabetic patients. The study hopes to collect evidence on which one of these treatment strategies is most effective.

    To take part in this study patients must be 65 years old or more and have a diagnosis of Type 2 Diabetes Mellitus. Each participant will be in the study for 72 weeks (about a year and a half) and the whole study is due to last for just over 4 years.

    Study assessments will include: Physical examinations, completion of study diaries and questionnaires and blood and urine tests.

  • REC name

    Yorkshire & The Humber - Sheffield Research Ethics Committee

  • REC reference

    14/YH/0005

  • Date of REC Opinion

    5 Feb 2014

  • REC opinion

    Further Information Favourable Opinion