Immune Responses in Human Tonsils (Version 1.0)

• Research type

  Research Study

• Full title

  How T follicular helper T cells support B cell responses in humans

• IRAS ID

  196604

• Contact name

  Michelle A Linterman

• Contact email

  Michelle.linterman@babraham.ac.uk

• Sponsor organisation

  Babraham Institute

• Duration of Study in the UK

  4 years, 0 months, 1 days

• Research summary

  White blood cells respond to infection or immunisation by collaborating with each other in specialised anatomical structures such as the spleen, lymph nodes (e.g. tonsils). Here, they are able to generate immunity that can provide protection against subsequent infection. Sometimes, these processes break down, and can result in an impaired response after infection or vaccination. This study aims to understand the cellular and molecular biology that underpins both normal and impaired immune responses in humans.

• REC name

  London - Surrey Research Ethics Committee

• REC reference

  16/LO/0453

• Date of REC Opinion

  7 Mar 2016

• REC opinion

  Favourable Opinion