Immune cell dysfunction in hepatocellular carcinoma (HCC)

• Research type

  Research Study

• Full title

  The role of the host tumour and virus specific immunity in disease outcome in patients with hepatocellular carcinoma(HCC) with or without viral hepatitis infection.

• IRAS ID

  152971

• Contact name

  Abid Suddle

• Contact email

  abid.suddle@nhs.net

• Sponsor organisation

  Kings College Hospital NHS Foundation Trust

• Duration of Study in the UK

  2 years, 2 months, 30 days

• Research summary

  In this study we will investigate the relationship between a patient's immune system and the liver tumour. We will perform a series of laboratory experiments to determine the role of different immune cells in the processes contributing to cancer regression or progression. We will also look at the effect of new treatment regimens on the patient's immune responses to the tumour.

• REC name

  Yorkshire & The Humber - Sheffield Research Ethics Committee

• REC reference

  17/YH/0154

• Date of REC Opinion

  11 May 2017

• REC opinion

  Favourable Opinion