Imaging heart repair following a heart attack

  • Research type

    Research Study

  • Full title

    Imaging cardiac repair following myocardial infarction using hyperpolarized 13C magnetic resonance imaging

  • IRAS ID

    192843

  • Contact name

    Damian Tyler

  • Contact email

    damian.tyler@dpag.ox.ac.uk

  • Sponsor organisation

    University of Oxford

  • Duration of Study in the UK

    1 years, 0 months, 1 days

  • Research summary

    Following a heart attack, the body initiates an intricate set of processes to reinforce the damaged area of heart muscle. We currently have no good way of measuring these repair processes, though work in laboratories suggests that an advanced new magnetic resonance scanning technique, hyperpolarized magnetic resonance, could do this. We are therefore performing a study of hyperpolarized magnetic resonance imaging in people who have had a recent heart attack. We plan to ask 10 people who have had a recent heart attack treated at the John Radcliffe Hospital in Oxford to take part, and to undergo up to 4 MRI scans over 2 months. We hope that by being able to assess the repair processes non-invasively that it will be possible to improve our understanding of heart attacks. The work is funded by the NIHR Oxford BRC and the BHF.

  • REC name

    South Central - Oxford B Research Ethics Committee

  • REC reference

    16/SC/0146

  • Date of REC Opinion

    19 Apr 2016

  • REC opinion

    Further Information Favourable Opinion