Imaging and genetic insights into the human visual system (IMGEN)
Research type
Research Study
Full title
Genetic and imaging insights into the human visual system (IMGEN)
IRAS ID
346793
Contact name
Panagiotis Sergouniotis
Contact email
Sponsor organisation
University of Manchester
Duration of Study in the UK
3 years, 2 months, 1 days
Research summary
Advances in imaging technologies have enabled detailed assessment of the processes that drive conscious vision in humans. For example, through the use of high-resolution retinal imaging it is now possible to establish a more comprehensive understanding of how the key structures at the back of the eye develop and are disrupted during aging and disease.
With the overarching aim of studying the visual system and its pathology from molecules to behaviour, we will perform a set of investigations (including detailed retinal imaging and genetic analyses) in healthy volunteers and in people with reduced vision (including individuals with genetic retinal conditions). The impact of both genetic and non-genetic factors (e.g. premature birth) on visual system structure and function will be evaluated.
The study will last 38 months and recruitment will be at the Manchester University NHS Foundation Trust and at the University of Manchester.
This work will: (i) provide insights into how the visual system develops; (ii) highlight key disease biomarkers; and (iii) provide a framework for understanding the potential of emerging therapies.
REC name
North West - Haydock Research Ethics Committee
REC reference
24/NW/0377
Date of REC Opinion
30 Dec 2024
REC opinion
Further Information Favourable Opinion