Imaging and electrophysiology of gait changes in Parkinson's disease
Research type
Research Study
Full title
Investigating the link between cognition and gait impairments in Parkinson's disease using MRI surrogate markers of the cholinergic system and mobile EEG
IRAS ID
250729
Contact name
Nicola Ray
Contact email
Sponsor organisation
Manchester Metropolitan University
Duration of Study in the UK
1 years, 6 months, 1 days
Research summary
People with Parkinson's disease (PD) often experience both cognitive and gait impairments. The current research aims to understand the link between these using brain imaging and mobile EEG (brain signals recorded while people are freely moving). We believe that a fuller understanding of the changes in these brain regions will enable earlier, and more accurate, prediction of falls and cognitive decline in Parkinson's disease.
We will recruit 20 people with Parkinson's disease with a history of falls, 20 people with Parkinson's disease without a history of falls, and 20 age-matched controls. All will undergo mobile EEG and an MRI scan, alongside gait and cognitive assessment.
REC name
North West - Greater Manchester West Research Ethics Committee
REC reference
19/NW/0279
Date of REC Opinion
1 Jul 2019
REC opinion
Further Information Favourable Opinion