Image guidance for children with brain tumours undergoing surgery
Research type
Research Study
Full title
A tailored image guidance approach for children undergoing surgery for brain tumours
IRAS ID
332150
Contact name
Jonathan Clayden
Contact email
Sponsor organisation
UCL Great Ormond Street Institute of Child Health
Clinicaltrials.gov Identifier
Z6364106/2024/02/147, UCL Data Protection Office registration number
Duration of Study in the UK
1 years, 9 months, 31 days
Research summary
Modern neuroimaging is an extremely valuable navigational tool for neurosurgical teams. Submodalities of magnetic resonance imaging (MRI) can help identify and track important anatomical and clinical landmarks for surgical planning and intraoperative updating. This project will bring clinicians and basic scientists together to test and evaluate a promising development to diffusion MRI analysis that offers rapid, robust and uncomplicated segmentation of surgically important white matter structures, even in the presence of substantial tissue distortion, with the ultimate aim of overlaying them within neuronavigation systems to aid surgeons and help improve patient outcomes. We plan to recruit a series of children undergoing surgery for different types of brain tumours, run the new tool on their clinically acquired MRI scans, evaluate its performance in different tumour types and make improvements to broaden its applicability.
REC name
West Midlands - Solihull Research Ethics Committee
REC reference
24/WM/0071
Date of REC Opinion
9 May 2024
REC opinion
Further Information Favourable Opinion