Iluvien for IRD

• Research type

  Research Study

• Full title

  A Pilot Study Evaluating the Effect of Intravitreal Fluocinolone Acetonide (0.19mg) in Patients with Retinitis Pigmentosa

• IRAS ID

  201774

• Contact name

  Kamron Khan

• Contact email

  kamron.khan@moorfields.nhs.uk

• Sponsor organisation

  Moorfields Eye Hospital

• Eudract number

  2016-002523-28

• Duration of Study in the UK

  3 years, 3 months, 31 days

• Research summary

  Retinitis Pigmentosa (RP) is the term used to describe a range of inherited retinal diseases. Individually they are rare, but collectively they now represent the major cause of blindness in working age adults. RP is characterised by signs of inflammation. Although the underlying mechanisms are poorly understood, activating the inflammatory cascade is thought to exacerbate cell death. In this pilot study we will test the efficacy of Iluvien, a commonly used intraocular steroid, to reduce the inflammatory response in selected patients with RP. In doing so we hope to (a) slow the rate of visual loss, and (b) identify objective parameters for monitoring disease progression.

• REC name

  London - Harrow Research Ethics Committee

• REC reference

  16/LO/1319

• Date of REC Opinion

  16 Sep 2016

• REC opinion

  Further Information Favourable Opinion