Interstitial Lung Disease DNA Study
Imperial College London
Duration of Study in the UK
5 years, 0 months, 0 days
Pulmonary fibrosis or Interstitial Lung Disease (ILD) encompasses a wide spectrum of progressive and irreversible disorders destruction of the lung. Clinically this causes cough and progressive breathing difficulty, which in the majority of cases result in death. Currently, diagnosis is challenging, with a third of patients either falling outside of the current disease categories or are termed unclassifiable.
Recent studies have highlighted similarities in genetic predisposition across a range of ILDs. The pipeline from the genetic makeup of an individual to proteins that are constructed from these genes can be viewed as a disease ‘fingerprint’ and scientific discovery along this path can lead to new understanding of pathogenesis.
We hope to identify specific markers in the blood of patients with a range of ILDs that will sidestep conventional classifications, speeding up the diagnostic pathway and avoid some of the more invasive diagnostic tests currently being used in clinical practice.
London - City & East Research Ethics Committee
Date of REC Opinion
10 Nov 2022
Further Information Favourable Opinion