Identification of foreign protein in rheumatological disease Version 1
Research type
Research Study
Full title
Identification of the foreign protein component of immune complexes in rheumatological disease
IRAS ID
100709
Contact name
Adam Taylor
Contact email
Sponsor organisation
Lancaster University
Duration of Study in the UK
1 years, 7 months, 29 days
Research summary
Rheumatoid Arthritis(RA) is a disease that affects over 500,000 people in the UK alone and causes swelling and damage to joints. RA is an autoimmune disease, where the body attacks itself. The underlying cause of this disease is still unknown as yet there is no effective treatment. This research aims to examine patient urine samples to look to identify proteins that may be responsible for RA and potentially open up new opportunities for understanding and treating the disease. This study will analyse urine from patients with and without RA to look for proteins that may contribute to the formation of the disease. This analysis will consist of mass spectrometry, ELISA and western blotting. RA patients and control subjects will be asked to complete an anonymised questionnaire regarding lifestyle and health.
REC name
North West - Preston Research Ethics Committee
REC reference
15/NW/0038
Date of REC Opinion
17 Feb 2015
REC opinion
Favourable Opinion