Identification of Cognitive Impairment in Longitudinal Ageing Study
Research type
Research Study
Full title
Identification of cognitive impairment in volunteers of the Manchester Longitudinal Research study of Cognition in Healthy Older Adults
IRAS ID
188679
Contact name
Neil Pendleton
Contact email
Sponsor organisation
Salford Royal NHS Foundation Trust
Duration of Study in the UK
0 years, 10 months, 30 days
Research summary
The University of Manchester Longitudinal study of cognition in healthy older adults has studied cognitive ageing for more than 25 years and provides a resource for understanding cognitive ageing. Despite expected attrition due to withdrawal or death, there are still over 500 participating volunteers available who have agreed to remain part of this research. We propose to enhance this by identification of which volunteers suffer from cognitive impairment before death using a post-mortem standardised information form to identify which develop cognitive impairment or dementia. We will ask nominated informants to alert us to their death and answer a validated questionnaire to identify cognitive impairment. We will also ask their GP whether the volunteer had any known diagnosis of disorders such as Mild Cognitive Impairment or Dementia. Having this information will allow fuller interpretation of the longitudinal data which can then be considered in context of whether a volunteer had cognitive impairment or dementia ever. This may provide opportunity to examine the earlier data for possible risk profiles for development of late life dementia
REC name
HSC REC B
REC reference
16/NI/0068
Date of REC Opinion
12 Apr 2016
REC opinion
Favourable Opinion