IDEAS - (Identification of DEterminants of Altered circadian rhythms)
Research type
Research Study
Full title
Evaluation of objective and patient-reported determinants of disruption of the circadian rest-activity rhythm (low Dichotomy Index I<O); Propaedeutic multicenter observational study.
IRAS ID
233972
Contact name
Francis Levi
Contact email
Sponsor organisation
University of Warwick
Duration of Study in the UK
0 years, 5 months, 16 days
Research summary
This is a multicentre observational study aiming to discover the modifiable factors that cause circadian rhythms (body clocks) to be disrupted in patients with locally advanced or metastasised cancer of the colon, rectum, pancreas, stomach or biliary tract.
The study will use a number of tele-monitoring techniques, saliva samples and self-reported questionnaires to measure each participant’s circadian rhythm alongside symptom burden, activity levels, quality of life, perceived sleep patterns and mental well-being.
Participants will use electronic monitoring equipment at home, complete questionnaires and provide saliva samples alongside the electronic monitoring.The results will then be analysed to establish any correlates of poor circadian rhythm that may be amenable to improvement via targeted interventions.
REC name
East Midlands - Leicester Central Research Ethics Committee
REC reference
17/EM/0422
Date of REC Opinion
16 Nov 2017
REC opinion
Further Information Favourable Opinion