ICRT project

• Research type

  Research Study

• Full title

  Evaluation of the effects of Intrastromal Implantation of Posterior Corneal Lamellae for the treatment of moderate to advanced Keratoconus

• IRAS ID

  263155

• Contact name

  Abdo Karim Tourkmani

• Contact email

  karim.tourkmani2@wales.nhs.uk

• Sponsor organisation

  Aneurin Bevan University Health Board

• Duration of Study in the UK

  1 years, 0 months, 0 days

• Research summary

  Keratoconus is a corneal disorder where the cornea becomes "cone shaped". This protocol aims to demonstrate that the corneal transplant method: Intrastromal Implantation of Posterior Corneal Lamellae (IIPCL) is same or as effective as Bowman Layer Transplant (BLT) or intrastromal implantation of decellularized stromal lamellae (IIDSL) in terms of risks and benefits for the patient.
  The main advantage of IIPCL over BLT would be that donor tissue wastage would be negligible in IIPCL, compared to 30% in BLT.
  The main advantage of IIPCL over IIDSL would be that IIPCL is much less expensive (doesn’t require either a femto-laser or a decellularization protocol).
  In the long term, it would be less expensive than traditional forms of treatment such as penetrating keratoplasty or DALK, and much better for the patient.

• REC name

  Wales REC 2

• REC reference

  19/WA/0260

• Date of REC Opinion

  18 Sep 2019

• REC opinion

  Unfavourable Opinion