ICG-AOSLO
Research type
Research Study
Full title
Developing an Indocyanine Green dye detection optimised adaptive optics scanning laser ophthalmoscope
IRAS ID
354242
Contact name
Colin Chu
Contact email
Sponsor organisation
Moorfields Eye Hospital NHS Foundation Trust
Duration of Study in the UK
0 years, 4 months, 1 days
Research summary
The aim of this study is to test a custom research tool that can image part of the living human eye called the retina to an exceptional level of detail. It is called an ‘Adaptive Optics Scanning Laser Ophthalmoscope', shortened to AOSLO. Instruments like this have already been used for many years on patients, but this one is specially designed to detect a dye called Indocyanine Green (ICG) that is given routinely in the eye clinic.
We will invite patients being given ICG already on the day of their routine clinic appointment to have an extra 30-60 minutes of images taken using the custom AOSLO research tool.
If successful, we hope to deploy the AOSLO in future studies where we could use ICG to label immune cells and see if they can be identified and measured to better understand different eye diseases.
REC name
West of Scotland REC 5
REC reference
25/WS/0107
Date of REC Opinion
8 Jul 2025
REC opinion
Favourable Opinion