IBDminds
Research type
Research Study
Full title
Mapping the influence of anxiety and depression on patients with IBD
IRAS ID
357218
Contact name
P Harvey
Contact email
Sponsor organisation
The Royal Wolverhampton NHS Trust
Duration of Study in the UK
2 years, months, days
Research summary
People with Inflammatory bowel disease (IBD) can get challenging symptoms. Things like diarrhoea, tummy pain and being tired all the time are common. People often get IBD in their teens or twenties. They often find working, studying and relationships hard. IBD can’t be cured, so it lasts for life.
When IBD is hard to treat, we use advanced treatments, but these don’t always work. When they do work the effect can wear off. This happens in 2 of 5 people within a year in research studies. There are some things that we know make them wear off. There are lots more reasons that we don’t understand yet. We think anxiety, depression and stress make these treatments more likely to wear off. Previous research has suggested that people with IBD do worse if they have anxiety, depression or stress.
We want people with IBD to complete questionnaires to see if they are affected by anxiety, depression or stress when they are taking advanced therapies. We will follow those people to see if the effect of their treatment wears off.
People living with IBD will contribute to the running and fine tuning of this research. Many of those that have engaged with us so far have said that their disease was worse when their mental health was worse. They were generally supportive of this study to see how anxiety, depression and stress effects IBD in people using advanced therapies.
We have talked to a national charity about our work. They will help us share our findings so that patients, care givers and other stakeholders will be able to read about them. We will also publish our results so that doctors and researchers can use them.
REC name
London - Stanmore Research Ethics Committee
REC reference
25/PR/1298
Date of REC Opinion
18 Nov 2025
REC opinion
Further Information Favourable Opinion