IBD distress and medication adherence
Research type
Research Study
Full title
Investigating the association between IBD distress and medication adherence in patients with Crohn's Disease and Ulcerative Colitis.
IRAS ID
239755
Contact name
Christine Norton
Contact email
Sponsor organisation
King's College London
Duration of Study in the UK
0 years, 9 months, 0 days
Research summary
Inflammatory Bowel Disease is a term used to describe two life-long conditions that affect the bowels: Crohn's Disease and Ulcerative Colitis. IBD can cause a number of symptoms like bloody diarrhoea, pain and weight loss. Medical treatment (oral medications, injections or infusions) is often required for long periods of time.
When medications have to be taken for a long time, patients often struggle in complying with medical recommendations. This can cause worsening of symptoms and can lead to more invasive treatment like surgery, affecting not only patients' quality of life, but also health economics due to the high cost of hospital admissions and treatments.Research has found that medication adherence is affected by psychological factors such as stress, anxiety and depression. The study's aim is to determine if there is an association between IBD-specific distress and medication adherence. The secondary aim of the study is to better understand the relationship that IBD patients have with their medications and what issues they encounter with long-term treatment. We are hoping that results from this study will give us a better understanding of the factors that affect medication adherence, contributing to future research aimed at improving IBD patients' quality of life.
The study will try to answer these questions through written questionnaires that will be administered three times over a period of six months and one to one interviews.
REC name
Yorkshire & The Humber - Bradford Leeds Research Ethics Committee
REC reference
18/YH/0224
Date of REC Opinion
7 Jun 2018
REC opinion
Favourable Opinion