I6Q-MC-BIFC Subcutaneous Buffer Injections in Healthy Subjects
Research type
Research Study
Full title
Protocol I6Q-MC-BIFC- A Randomized Study of Subcutaneous Injections of Buffer Matrices in Healthy Subjects
IRAS ID
236695
Contact name
Firas Almazedi
Contact email
Sponsor organisation
Eli Lilly and Company
Duration of Study in the UK
0 years, 3 months, 2 days
Research summary
Pain from subcutaneous (SC) injections (an injection under the skin) of medications is common and can discourage people from taking their medication. What may contribute to the pain experienced with injected medications is the buffer (a substance that is used to help the drug be absorbed into the body) that is given with the medication, as different buffers with varying strengths can be used.
This study is being carried out to compare the amount of pain at the injection-site between 3 different types of buffer at different strengths. This could help to improve future medications by reducing the amount of pain people experience with injectable medications.
The buffers injected in this study will contain inactive ingredients only. Participants will not receive any drug in this Study.
Up to 55 participants will be participating in this study. The total study duration will be up to 7 weeks from the time of screening to the last follow-up.REC name
North West - Greater Manchester West Research Ethics Committee
REC reference
17/NW/0696
Date of REC Opinion
8 Dec 2017
REC opinion
Favourable Opinion