Hypotrain
Research type
Research Study
Full title
Hypotrain - improvement of safety and knowledge of exercise and type 1 diabetes
IRAS ID
257851
Contact name
Peter Kristensen
Contact email
Sponsor organisation
Sheffield Teaching Hospitals NHS Foundation Trust
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
Regular physical activity is associated with a range of health-related benefits in type 1 diabetes (T1DM) and is recommended as an integrated part of diabetes treatment. In people with T1DM, exercise can lead to unwanted blood glucose fluctuations – especially low glucose, which elicit frustration for the patient and potentially is lethal. This may stop patients from doing exercise, thereby missing health benefits.
Many factors affect glucose levels during and after exercise. The effect-size of each of these factors are unknown, especially during real life exercise. Therefore, it is very difficult for patients and health care professionals to foresee and prevent low glucose during and after exercise.
To reduce the burden of exercise related problems in persons with T1DM – and thereby stimulate long term reduction of cardiovascular disease and overweight - the objective of this questionnaire based research project is to answer the following questions:
What kind of exercise do people with T1DM perform and to what extent?
What are the obstacles for doing exercise for people with type 1 diabetes?
How do people with type 1 diabetes manage exercise?Background information on demographic and diabetes variables.
Our hypothesis is that different exercise modalities modify blood glucose levels differently. The results of the studies will improve medical counselling about exercise to people with T1DM. Together, the results can reduce the burden of
exercise related problems in T1DM, thereby potentially reducing risk of cardiovascular disease.Please note that the submitted protocol covers clinical research activity to be undertaken in the UK and in Denmark. Study 2 & Study 3 described in the protocol will take place in Denmark only and so do not require review by UK NHS REC and HRA and are not described in this IRAS application form. The UK will take part in only Study 1
REC name
West Midlands - Solihull Research Ethics Committee
REC reference
19/WM/0126
Date of REC Opinion
12 Apr 2019
REC opinion
Favourable Opinion