HypoIQ

• Research type

  Research Study

• Full title

  Effects of FloTrac IQ on changing clinician behaviour in the management of intraoperative hypotension

• IRAS ID

  241508

• Contact name

  Simon Davies

• Contact email

  simon.davies@york.nhs.uk

• Sponsor organisation

  York Teaching Hospitals NHS Trust

• Duration of Study in the UK

  1 years, 0 months, 0 days

• Research summary

  Low blood pressure during surgery is a common problem, and over half of patients experienced a drop in their blood pressure greater than 40% from the starting number and this has been shown in a number of studies.

  In a study of over 33 000 patients undergoing major surgery, a mean arterial pressure (MAP) of less than 55 mmHg was associated with both kidney and heart injury and the risk increased with the amount of time spent below this blood pressure.
  
  More recent work has added to this evidence looking at the association of kidney injury and intraoperative low blood pressure in planned (elective) surgery. There was a relationship between low blood pressure both in terms of its severity and how long it lasted and the risk of kidney injury.
  There is now technology that works off a standard arterial line (drip placed into an artery in the wrist) that is able to predict low blood pressure before it happens, this is called the hypotension prediction index (HPI), and the rationale is that by using the HPI and the information it provides low blood pressure during surgery can be reduced and treated correctly. However, low blood pressure can also be avoided simply by asking the treating doctor to keep the blood pressure at the appropriate level, although the treatments may be inappropriate to the cause of low blood pressure and they may or may not do this in a timely manner. Therefore we aim to show that through the use of the HPI and the information it provides the behaviour of doctors to the treating of low blood pressure is changed compared to standard practice.

• REC name

  Yorkshire & The Humber - Sheffield Research Ethics Committee

• REC reference

  18/YH/0185

• Date of REC Opinion

  23 Nov 2018

• REC opinion

  Further Information Favourable Opinion