Human Intracortical Brain-Computer Interface
Research type
Research Study
Full title
Exploring implanted Brain-Computer Interfaces to restores sensorimotor and cognitive function
IRAS ID
324147
Contact name
Luke Bashford
Contact email
Sponsor organisation
The Newcastle upon Tyne Hospitals NHS Foundation Trust
Duration of Study in the UK
4 years, 0 months, 28 days
Research summary
The proposed basic science study with human participants seeks to develop an implanted Brain-Computer Interface (iBCI), termed the UK Neural Prosthetic System (UK-NPS). The device aims to restore sensorimotor and cognitive functions to individuals who have lost this due to the severe neurological conditions of motor neurone disease and spinal cord injury and reveal new features of the neural signal that can be used to improve the treatment of these and other conditions. The device will be implanted in areas of the brain responsible for sensorimotor and cognitive function. The iBCI will be used to both record and stimulate specific populations of neurons in the brain by delivering pulses of electrical stimulation. The brain activity that underlies movement, sensation and cognitive control will be identified and then used to allow participants sensorimotor and cognitive control over digital devices. For example, when a user imagines or attempts behaviours that they cannot perform due to the neurological condition, these will be recognised by the iBCI and realised through digital devices. By using ICMS in the cortex, we will provide neuromodulation of the brain state and thus restore cognitive and somatosensory function, providing feedback and improved performance. The aim of restoring sensorimotor and cognitive deficits, a critical unmet need for those living with spinal cord injury and motor neurone disease has been identified, highlighted and co-created in extensive PPIE work over many years, with national and international input. Demonstration of successful iBCI use will retore personhood and greatly improve the quality of life for these individuals and advance our understanding of the human brain to identify novel treatment options for people with lived experience of sensorimotor and cognitive deficits.
REC name
North West - Greater Manchester South Research Ethics Committee
REC reference
26/NW/0135
Date of REC Opinion
13 Jul 2026
REC opinion
Further Information Favourable Opinion