Human Immune Responses to AMR Pathogens
Research type
Research Study
Full title
Investigating Human Functional Immune Responses to Antimicrobial Resistant Pathogens (h-ARP)
IRAS ID
290629
Contact name
Thomas C Darton
Contact email
Sponsor organisation
Sheffield Teaching Hospitals NHS Foundation Trust
Duration of Study in the UK
1 years, 11 months, 31 days
Research summary
Infections caused by bacteria are very common and often need treatment with antibiotics and occasionally hospital admission. Once people are admitted to hospital, in some cases it is becoming harder to find an effective antibiotic to use for treatment. The main reason for this is the increase in bacteria which are resistant to antibiotics and aren’t effectively killed by them. In some cases, there are few antibiotic options available and those that are left are associated with more side effects.
Because of the increase in antibiotic resistance (AMR), both in the UK and around the world, we are keen to identify new ways of preventing and treating these types of infection. One way of doing this is to study how people who have infection use their immune system to effectively fight it off. Identifying the active components of an effective immune response might help us to develop new vaccines to prevent infection or treatments which are more effective than antibiotics.REC name
Yorkshire & The Humber - Sheffield Research Ethics Committee
REC reference
20/YH/0335
Date of REC Opinion
18 Jan 2021
REC opinion
Further Information Favourable Opinion