How does PCF relate to spirometry in lung transplantation?

  • Research type

    Research Study

  • Full title

    A cross sectional feasibility study examining the relationship between peak cough flow and respiratory function testing (spirometry) post bilateral sequential single lung transplantation, at a single centre cardiothoracic transplantation unit.



  • Contact name

    Anna Reed

  • Contact email

  • Sponsor organisation

    Royal Brompton and Harefield NHS Foundation Trust

  • Duration of Study in the UK

    0 years, 5 months, 27 days

  • Research summary

    This study aims to look at an individuals cough strength (as measured by a portable peak cough flow device called a Mini Wright’s Low Range Peak Flow Meter™ attached to a face mask) in relation to their lung function, of which spirometry is currently the gold standard measurement. It will aim to recruit 30 participants who are at least 1 month post double lung transplantation at a single centre transplant unit, Harefield Hospital. The study is being conducted as part of a masters of clinical research project and due to the complexity of the outpatient clinic and given that no research has ever been done in this particular field, the study will be conducted as a feasibility study. Baseline data and health related quality of life scores will also be recorded to establish if these is any relationship between lung function and these markers. This small study will help to plan a larger study which may then go on to help identify patients at risk of developing respiratory infections at an earlier date and highlight them as candidates for a more individualised respiratory physiotherapy programme.

  • REC name

    West Midlands - South Birmingham Research Ethics Committee

  • REC reference


  • Date of REC Opinion

    15 Mar 2017

  • REC opinion

    Favourable Opinion

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